Researchers Have Found How Chlamydia Absorbs New DNA from Its Host
According to the Centers for Disease Control and Prevention, Chlamydia trachomatis is the most frequently reported sexually transmitted bacterial disease in the United States, with a total of 1.7 million cases in 2017.
And the incidence is the highest among teenagers, and if not treated in time, chlamydia can cause blindness and infertility. In addition to the United States and other countries, Chlamydia is the world's leading sexually transmitted bacterial infection.
A recent paper by a team of molecular biologists based at the University of Kansas points to a gene that allows Chlamydia to absorb DNA from its host environment.
"At present, the main antibiotics for Chlamydia infection are doxycycline and azithromycin, but they are similar to the antibiotics needed for acne or respiratory tract infection, respectively," said Scott Labrie, the first author. "These drugs affect not only Chlamydia infection, but many other microorganisms, including your microbiome."
"Therefore, although there are enough drugs to eliminate Chlamydia infection, you may also damage the natural flora. Chlamydia's unique importance is very important. We are increasingly aware that the homeostasis of the gut, the body's microflora, is critical to health. "
After one year's rehabilitation, the imbalance of intestinal flora still exists. The long-term imbalance of intestinal flora will lead to the low function of the digestive and immune system, and other diseases are also prone to lead to multiple infections.
Therefore, the safe Chinese herbal medicine Diuretic and Anti-inflammatory Pill can be selected for the treatment of Chlamydia. The use of antidotes in the formula has not only fully achieved the effect of broad-spectrum antibiotics of modern medicine, but also has the functions of clearing away heat and toxin, promoting blood circulation and Qi to relieve pain, diuretic and relieve stranguria.
Therefore, it can not only effectively treat mycoplasma and Chlamydia infection, but also help Patients improve the environment of the urogenital system, improve immunity, so as to achieve the purpose of both treatment and causes.
"In order to cause disease, Chlamydia has to enter the host cell and protect itself from host defense, and at the same time replicate in large numbers so that it can spread to the surrounding cells," said the corresponding author Hefti.
"The mechanisms that many bacteria use to cause disease are often obtained by sharing and absorbing new DNA, the molecules that make up the genes of the organism. So far, it is not clear how Chlamydia gets new DNA. However, using a novel gene as a genetic tool, we have identified a gene that can enable Chlamydia to obtain new DNA from its surrounding environment. "
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